Failed to make connection to backend after upgrade to nexus 3.78.2

Sonatype Nexus Repository
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Hello there,

I am currently testing the upgrade of our nexus from 3.77.2 to 3.78.2 on a preprod environment and after the upgrade, the URL of our nexus gives a “404 not found” and in the apache log I found the error “failed to make connexion to backend”.
The nexus is installed on a debian 12 lxc container, I’ve used the nexus-unix-x86-64 package and had to follow this discussion to make the nexus start :
Shell Compatibility Issue in Nexus Repository 3.78.2-04 Startup Script (I’ve replaced the first line of the nexus bin file with “#!/bin/bash”)

Nexus sonatype start and doesn’t have any error in its log files, only our apache proxy has some logs. Any of you encountered this problem ? I don’t see anything unusual in our apache conf file that has always worked and I have the same error if I try to upgrade to nexus 3.82.0 with the linux x86_64 package. There is no issue with the database connection.

Here is our apache configuration file with anonymisation :

<VirtualHost *:443>
        ServerName <DNS hostname>
        ServerSignature Off
        RewriteEngine on
        RewriteCond %{REQUEST_METHOD} ^(TRACE|TRACK)
        RewriteRule .* - [F]

        ProxyRequests Off
        ProxyPreserveHost On
        ProxyTimeout 300
        ProxyPass /nexus http://localhost:8081/nexus nocanon
        ProxyPassReverse /nexus http://localhost:8081/nexus

        Header edit Location ^http://(.*)$ https://$1
        RequestHeader set X-Forwarded-Proto "https"
        RequestHeader set X-Forwarded-Port "443"

        <Location />
                Order deny,allow
                Allow from all
        </Location>

        AllowEncodedSlashes NoDecode
        SSLEngine On
        RequestHeader set X_FORWARDED_PROTO 'https'

        SSLCertificateFile      <path/to/file>
        SSLCertificateKeyFile   <path/to/file>
        SSLCertificateChainFile <path/to/file>

        # HSTS (mod_headers is required) (15768000 seconds = 6 months)
        Header always set Strict-Transport-Security "max-age=15768000"

        ErrorLog /var/log/apache2/<filename>.log
        LogLevel warn
        CustomLog /var/log/apache2/<filename>.log combined

</VirtualHost>

Thanks,